Personnel Information

写真b

OOTANI Kiyoshi

Organization
School of Biological and Environmental Sciences Department of Biomedical Sciences
Research Fields, Keywords
生命医化学
Teaching and Research Fields
細胞増殖制御、癌化、転写制御
SDGs Related Goals

Degree 【 display / non-display

  • Degree name:Medical Doctor
    Classified degree field:Life Science / Human pathology
    Conferring institution:Tohoku University
    Acquisition way:Coursework
    Date of acquisition:1989.03

Career 【 display / non-display

  • Affiliation:Kwansei Gakuin University
    Title:Professor
    Date:2009.04 -

Association Memberships 【 display / non-display

  • Academic society name:日本分子生物学会
    Academic country located:Japan

  • Academic society name:日本癌学会
    Academic country located:Japan

  • Academic society name:日本ウイルス学会
    Academic country located:Japan

Research Areas 【 display / non-display

  • Research field:Life Science / Molecular biology

Papers 【 display / non-display

  • Language: English
    Title: Expanding Roles of the E2F-RB-p53 Pathway in Tumor Suppression
    Journal name: Biology (Basel)  vol.12  (12)  (p.1511 - )
    Date of publication: 2023.12
    Author(s): Zhou Y, Nakajima R, Shirasawa M, Fikriyanti M, Zhao L, Iwanaga R, Bradford AP, Kurayoshi K, Araki K, Ohtani K

    DOI: 10.3390/biology12121511
    Type of publication: Research paper (scientific journal)
    Field of experts:Life Science / Molecular biology

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  • Language: English
    Title: Deregulated E2F activity as a cancer-cell specific therapeutic tool
    Journal name: Genes (Basel)  vol.14  (2)  (p.393 - )
    Date of publication: 2023.02
    Author(s): Rinka Nakajima, Lin Zhao, Yaxuan Zhou, Mashiro Shirasawa, Ayato Uchida, Hikaru Murakawa, Mariana Fikriyanti, Ritsuko Iwanaga, Andrew P. Bradford, Keigo Araki, Tomoko Warita and Kiyoshi Ohtani

    DOI: 10.3390/genes14020393
    Type of publication: Research paper (scientific journal)
    Field of experts:Life Science / Molecular biology

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  • Language: English
    Title: Mitochondrial protein E2F3d, a distinctive E2F3 product, mediates hypoxia-induced mitophagy in cancer cells
    Journal name: Communications Biology  vol.2  (p.3 - )
    Date of publication: 2019.01
    Author(s): Araki K, Kawauchi K, Sugimoto W, Tsuda D, Oda H, Yoshida R, Ohtani K

    DOI: 10.1038/s42003-018-0246-9
    Type of publication: Research paper (scientific journal)
    Field of experts:Life Science / Molecular biology

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  • Language: English
    Title: Differential requirement for dimerization partner DP between E2F-dependent activation of tumor suppressor and growth-related genes
    Journal name: Scientific Reports  vol.8  (1)  (p.8438 - )
    Date of publication: 2018.05
    Author(s): Komori H, Goto Y, Kurayoshi K, Ozono E, Iwanaga R, Bradford P, Araki K and Ohtani K

    DOI: 10.1038/s41598-018-26860-0
    Type of publication: Research paper (scientific journal)
    Field of experts:Life Science / Molecular biology

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  • Language: English
    Title: Engineered Polymeric Nanovector for Intracellular Peptide Delivery in Antitumor Therapy
    Journal name: Int J Nanomedicine  vol.18  (p.5343 - 5363)
    Date of publication: 2023.09
    Author(s): Xi Zhang, Mingming Zhang, Sijun Huang, Kiyoshi Ohtani, Li Xu, Yi Guo

    DOI: 10.2147/IJN.S427536
    Type of publication: Research paper (scientific journal)
    Field of experts:Life Science / Molecular biology

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Industrial Property Rights 【 display / non-display

  • Property type:Patent
    Title:がん細胞標的ベクター、がん細胞特異的に目的遺伝子を発現させる方法及びがん細胞特異的に目的遺伝子を発現させるための使用
    Inventor(s)/Creator(s):大谷清

    Application number:特願2016-514831, 2015.03.27
    Country:Japan

  • Property type:Patent
    Title:がん細胞標的ベクター、がん細胞特異的に目的遺伝子を発現させる方法及びがん細胞特異的に目的遺伝子を発現させるための使用
    Inventor(s)/Creator(s):大谷清

    Application number:PCT/JP2015/059699, 2015.03.27
    Country:

Research Projects 【 display / non-display

  • Research category:Grant-in-Aid for Scientific Research(C)
    Project year:2021.04 - 2024.03
    Title:がん化抑制に重要なRBの制御を外れたE2F1活性の制御メカニズムの解明

  • Research category:Grant-in-Aid for Scientific Research(C)
    Project year:2015.04 - 2018.03
    Title:転写因子E2Fによる細胞増殖とがん化抑制の仕分け機構の解明

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  • Project year:2012.11 - 2013.10
    Title:がん細胞特異性のより高いがん細胞傷害性組換えアデノウイルスの開発(研究成果展開事業 研究成果最適展開支援プログラムA-STEP探索タイプ)
    Awarding organization:独立行政法人科学技術振興機構

  • Research category:Grant-in-Aid for Scientific Research(C)
    Project year:2012.04 - 2015.03
    Title:転写因子E2Fによるがん化抑制機構の解析

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  • Research category:Grant-in-Aid for Scientific Research(C)
    Project year:2009.04 - 2012.03
    Title:細胞増殖と癌化抑制における転写因子E2Fによる細胞運命決定機構の解析

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