OOTANI Kiyoshi
Degree 【 display / non-display 】
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Degree name:Medical Doctor
Classified degree field:Life Science / Human pathology
Conferring institution:Tohoku University
Acquisition way:Coursework
Date of acquisition:1989.03
Career 【 display / non-display 】
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Affiliation:Kwansei Gakuin University
Title:Professor
Date:2009.04 -
Association Memberships 【 display / non-display 】
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Academic society name:日本分子生物学会
Academic country located:Japan -
Academic society name:日本癌学会
Academic country located:Japan -
Academic society name:日本ウイルス学会
Academic country located:Japan
Research Areas 【 display / non-display 】
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Research field:Life Science / Molecular biology
Papers 【 display / non-display 】
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Language: English
Title: Expanding Roles of the E2F-RB-p53 Pathway in Tumor Suppression
Journal name: Biology (Basel) vol.12 (12) (p.1511 - )
Date of publication: 2023.12
Author(s): Zhou Y, Nakajima R, Shirasawa M, Fikriyanti M, Zhao L, Iwanaga R, Bradford AP, Kurayoshi K, Araki K, Ohtani KDOI: 10.3390/biology12121511
Type of publication: Research paper (scientific journal)
Field of experts:Life Science / Molecular biology -
Language: English
Title: Deregulated E2F activity as a cancer-cell specific therapeutic tool
Journal name: Genes (Basel) vol.14 (2) (p.393 - )
Date of publication: 2023.02
Author(s): Rinka Nakajima, Lin Zhao, Yaxuan Zhou, Mashiro Shirasawa, Ayato Uchida, Hikaru Murakawa, Mariana Fikriyanti, Ritsuko Iwanaga, Andrew P. Bradford, Keigo Araki, Tomoko Warita and Kiyoshi OhtaniDOI: 10.3390/genes14020393
Type of publication: Research paper (scientific journal)
Field of experts:Life Science / Molecular biology -
Language: English
Title: Mitochondrial protein E2F3d, a distinctive E2F3 product, mediates hypoxia-induced mitophagy in cancer cells
Journal name: Communications Biology vol.2 (p.3 - )
Date of publication: 2019.01
Author(s): Araki K, Kawauchi K, Sugimoto W, Tsuda D, Oda H, Yoshida R, Ohtani KDOI: 10.1038/s42003-018-0246-9
Type of publication: Research paper (scientific journal)
Field of experts:Life Science / Molecular biology -
Language: English
Title: Differential requirement for dimerization partner DP between E2F-dependent activation of tumor suppressor and growth-related genes
Journal name: Scientific Reports vol.8 (1) (p.8438 - )
Date of publication: 2018.05
Author(s): Komori H, Goto Y, Kurayoshi K, Ozono E, Iwanaga R, Bradford P, Araki K and Ohtani KDOI: 10.1038/s41598-018-26860-0
Type of publication: Research paper (scientific journal)
Field of experts:Life Science / Molecular biology -
Language: English
Title: Engineered Polymeric Nanovector for Intracellular Peptide Delivery in Antitumor Therapy
Journal name: Int J Nanomedicine vol.18 (p.5343 - 5363)
Date of publication: 2023.09
Author(s): Xi Zhang, Mingming Zhang, Sijun Huang, Kiyoshi Ohtani, Li Xu, Yi GuoDOI: 10.2147/IJN.S427536
Type of publication: Research paper (scientific journal)
Field of experts:Life Science / Molecular biology
Industrial Property Rights 【 display / non-display 】
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Property type:Patent
Title:がん細胞標的ベクター、がん細胞特異的に目的遺伝子を発現させる方法及びがん細胞特異的に目的遺伝子を発現させるための使用
Inventor(s)/Creator(s):大谷清
Application number:特願2016-514831, 2015.03.27
Country:Japan
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Property type:Patent
Title:がん細胞標的ベクター、がん細胞特異的に目的遺伝子を発現させる方法及びがん細胞特異的に目的遺伝子を発現させるための使用
Inventor(s)/Creator(s):大谷清
Application number:PCT/JP2015/059699, 2015.03.27
Country:
Research Projects 【 display / non-display 】
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Research category:Grant-in-Aid for Scientific Research(C)
Project year:2021.04 - 2024.03
Title:がん化抑制に重要なRBの制御を外れたE2F1活性の制御メカニズムの解明
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Research category:Grant-in-Aid for Scientific Research(C)
Project year:2015.04 - 2018.03
Title:転写因子E2Fによる細胞増殖とがん化抑制の仕分け機構の解明
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Project year:2012.11 - 2013.10
Title:がん細胞特異性のより高いがん細胞傷害性組換えアデノウイルスの開発(研究成果展開事業 研究成果最適展開支援プログラムA-STEP探索タイプ)
Awarding organization:独立行政法人科学技術振興機構
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Research category:Grant-in-Aid for Scientific Research(C)
Project year:2012.04 - 2015.03
Title:転写因子E2Fによるがん化抑制機構の解析
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Research category:Grant-in-Aid for Scientific Research(C)
Project year:2009.04 - 2012.03
Title:細胞増殖と癌化抑制における転写因子E2Fによる細胞運命決定機構の解析