Personnel Information

写真b

NISHIMURA KENJI

Organization
School of Biological and Environmental Sciences Department of Biosciences
Research Fields, Keywords
オルガネラ, タンパク質分解, プロテアーゼ, 葉緑体
Research Outline
葉緑体は光合成をはじめとする植物の正常な発達や成長に欠かせない多くの代謝反応が行われる細胞内小器官（オルガネラ）です。葉緑体内には延べ数千種類にも及ぶタンパク質が存在し、これら生体反応を触媒しています。そのため植物はこれら葉緑体タンパク質の活性や機能を維持・制御することにより、葉緑体代謝を円滑に進める必要があります。特に高次構造の形成異常や損傷などにより機能不全を起こしたタンパク質や、細胞内外の環境変化によりそれ自体が不要になった場合は、分解除去される必要があります。この役割を担うのが葉緑体タンパク質分解酵素（プロテアーゼ）です。葉緑体内にはこれまでのところ少なくとも２０種類のプロテアーゼが存在することが知られています。我々はこれら葉緑体プロテアーゼのうち、どれがいつどこでどのタンパク質をなぜどのように分解しているかについて興味を持っています。また葉緑体タンパク質分解がどのような細胞内の現象と結びついているのか、さらに他のオルガネラを含む細胞内環境の変化と葉緑体タンパク質の恒常性との関連性についても明らかにしたいと考えています。
Syllabus information URL
https://syllabus.kwansei.ac.jp/uniasv2/UnSSOLoginControlFree?REQ_ACTION_DO=/AGA030PLS01Action.do?REQ_FUNCTION_JUMP_START_FLG=1&SLB_LINK_DISP_FLG=619&TCH_NO=196030&REQ_PRFR_FUNC_ID=AGA030
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Degree 【 display / non-display 】

  • Degree name:博士（バイオサイエンス）
    Classified degree field:Life Science / Plant molecular biology and physiology
    Conferring institution:Nara Institute of Science and Technology
    Acquisition way:Coursework
    Date of acquisition:2010.09

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Research Areas 【 display / non-display 】

  • Research field:Life Science / Plant molecular biology and physiology

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Papers 【 display / non-display 】

  • Language: English
    Title: Posttranslational Control of ALA Synthesis Includes GluTR Degradation by Clp Protease and Stabilization by GluTR-Binding Protein
    Journal name: Plant Physiology
    Date of publication: 2016.03
    Author(s): Janina Apitz, Kenji Nishimura, Judith Schmied, Anja Wolf, Boris Hedtke, Klaas J. van Wijk, Bernhard Grimm

    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

  • Language: English
    Title: Discovery of a Unique Clp Component, ClpF, in Chloroplasts: A Proposed Binary ClpF-ClpS1 Adaptor Complex Functions in Substrate Recognition and Delivery.
    Journal name: The Plant Cell
    Date of publication: 2015.11
    Author(s): Kenji Nishimura, Janina Apitz, Giulia Friso, Jitae Kim, Lalit Ponnala, Bernhard Grimm, Klaas J. van Wijk

    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

  • Language: English
    Title: Structures, Functions, and Interactions of ClpT1 and ClpT2 in the Clp Protease System of Arabidopsis Chloroplasts
    Journal name: The Plant Cell
    Date of publication: 2015.06
    Author(s): Jitae Kim, Matthew S. Kimber, Kenji Nishimura, Giulia Friso, Lance Schultz, Lalit Ponnala, Klaas J. van Wijk

    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

  • Language: English
    Title: The Clp protease system is required for copper ion-dependent turnover of the PAA2/HMA8 copper transporter in chloroplasts
    Journal name: New Phytologist
    Date of publication: 2014.12
    Author(s): Wiebke Tapken Jitae Kim Kenji Nishimura Klaas J. van Wijk Marinus Pilon

    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

  • Language: English
    Title: ClpS1 is a conserved substrate selector for the chloroplast Clp protease system in Arabidopsis
    Journal name: The Plant Cell
    Date of publication: 2013.07
    Author(s): Kenji Nishimura, Yukari Asakura, Giulia Friso, Jitae Kim, Soo-hyun Oh, Heidi Rutschow, Lalit Ponnala, Klaas J. van Wijk

    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

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MISC 【 display / non-display 】

  • Language:English
    Title:Essentials of Proteolytic Machineries in Chloroplasts
    Journal name:Molecular Plant
    Date of publication:2017.01
    Author(s):KenjiNishimuraYusukeKatoWataruSakamoto

    Type of publication:Article, review, commentary, editorial, etc. (scientific journal)

  • Language:English
    Title:Chloroplast Proteases: Updates on Proteolysis within and across Suborganellar Compartments
    Journal name:Plant Physiology
    Date of publication:2016.08
    Author(s):Kenji Nishimura, Yusuke Kato, Wataru Sakamoto

    Type of publication:Article, review, commentary, editorial, etc. (scientific journal)

  • Language:English
    Title:Organization, function and substrates of the essential Clp protease system in plastids
    Journal name:Biochimica et Biophysica Acta Bioenergetics
    Date of publication:2014.12
    Author(s):Kenji Nishimura, Klaas J.van Wijk

    Type of publication:Article, review, commentary, editorial, etc. (scientific journal)

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Research Projects 【 display / non-display 】

  • Research category:Grant-in-Aid for Research Activity start-up
    Project year:2019.08 - 2021.03
    Title:葉緑体タンパク質由来ペプチドによるシグナル伝達機構の解明

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