Personnel Information

写真b

TANAKA Masako

Organization
School of Biological and Environmental Sciences
Research Fields, Keywords
タンパク質恒常性, 分子シャペロン, 抗がん剤耐性, インタラクトーム
Teaching and Research Fields
 抗がん剤は治療初期には効果を示しますが、治療を続けるとやがて効果がなくなります。これを抗がん剤耐性と呼びますが、現在までに耐性を解除する治療薬は開発されていません。私たちはこれまでに分子シャペロンと結合するタンパク質を解析する独自の実験系を確立しています。本手法は遺伝子の発現変化を伴わないストレス応答機構を解明できる画期的な方法です。私たちはこの実験系を応用し、抗がん剤耐性の原因となる分子の探索や分子機構を解明する研究を展開しています。
Mail Address
tanakamsk@kwansei.ac.jp
SDGs Related Goals

Graduating School 【 display / non-display

  • Graduating School:Osaka City University
    Faculty:Faculty of Science
    Course / Major:生物学科

    Kind of school:University
    Date of graduation:2003.03
    Completion status:Graduated
    Country location code:Japan

Graduate School 【 display / non-display

  • Graduate school:Osaka City University
    Department:Graduate School, Division of Medicine
    Course:基礎医科学専攻

    Course completed:Doctor's Course
    Date of completion:2014.03
    Completion status:Completed
    Country:Japan

  • Graduate school:Osaka City University
    Department:Graduate School, Division of Natural Science
    Course:生物地球系専攻

    Course completed:Master's Course
    Date of completion:2005.03
    Completion status:Completed
    Country:Japan

Degree 【 display / non-display

  • Degree name:医学(博士)
    Classified degree field:Life Science / Pharmacology
    Conferring institution:Osaka City University
    Acquisition way:Coursework
    Date of acquisition:2014.03

  • Degree name:理学(修士)
    Classified degree field:Life Science / Animal physiological chemistry, physiology and behavioral biology
    Conferring institution:Osaka City University
    Acquisition way:Coursework
    Date of acquisition:2005.03

  • Degree name:理学(学士)
    Classified degree field:Life Science / Animal physiological chemistry, physiology and behavioral biology
    Conferring institution:Osaka City University
    Acquisition way:Coursework
    Date of acquisition:2003.03

Career 【 display / non-display

  • Affiliation:Kwansei Gakuin University
    Department:School of Biological and Environmental Sciences
    Title:Assistant Professor
    Date:2022.04 -

  • Affiliation:Waseda University
    Department:高等研究所
    Title:Assistant Professor
    Date:2018.04 - 2022.03

  • Affiliation:Waseda University
    Department:理工学術院 先進理工学部
    Title:Assistant Professor
    Date:2017.04 - 2018.03

  • Affiliation:Osaka City University
    Title:Assistant Professor
    Date:2014.04 - 2017.03

  • Title:Laboratory Assistant
    Date:2003.05 - 2008.06

Association Memberships 【 display / non-display

  • Academic society name:日本がん分子標的治療学会
    Academic country located:Japan

  • Academic society name:日本臨床ストレス応答学会
    Academic country located:Japan

  • Academic society name:日本癌学会
    Academic country located:Japan

  • Academic society name:日本薬理学会
    Academic country located:Japan

Research Areas 【 display / non-display

  • Research field:Life Science / Tumor biology

  • Research field:Life Science / Pharmacology

  • Research field:Life Science / Tumor diagnostics and therapeutics

Papers 【 display / non-display

  • Language: English
    Title: The Autophagy-Related Protein GABARAP Is Induced during Overwintering in the Bean Bug (Hemiptera: Alydidae).
    Journal name: Journal of economic entomology  vol.113  (1)  (p.427 - 434)
    Date of publication: 2020.02
    Author(s): Shin-Ichiro Tachibana, Shinji Matsuzaki, Masako Tanaka, Masayuki Shiota, Daisuke Motooka, Shota Nakamura, Shin G Goto

    DOI: 10.1093/jee/toz287
    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

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  • Title: Generation of Rat Monoclonal Antibodies Specific for Human Stromal Cell-Derived Factor-2.
    Journal name: Monoclonal antibodies in immunodiagnosis and immunotherapy  vol.39  (1)  (p.23 - 26)
    Date of publication: 2020.02
    Author(s): Tanaka M, Shiota M, Koyama M, Nakayama J, Yashiro M, Semba K, Goda N

    DOI: 10.1089/mab.2019.0043
    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

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  • Title: A dipeptidyl peptidase-4 (DPP-4) inhibitor, linagliptin, attenuates cardiac dysfunction after myocardial infarction independently of DPP-4.
    Journal name: Journal of pharmacological sciences  vol.139  (2)  (p.112 - 119)
    Date of publication: 2019.02
    Author(s): Yamaguchi T, Watanabe A, Tanaka M, Shiota M, Osada-Oka M, Sano S, Yoshiyama M, Miura K, Kitajima S, Matsunaga S, Tomita S, Iwao H, Izumi Y

    DOI: 10.1016/j.jphs.2018.12.004
    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

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  • Language: English
    Title: HIF-1-dependent lipin1 induction prevents excessive lipid accumulation in choline-deficient diet-induced fatty liver.
    Journal name: Scientific reports  vol.8  (1)  (p.14230)
    Date of publication: 2018.09
    Author(s): Takatomo Arai, Masako Tanaka, Nobuhito Goda

    DOI: 10.1038/s41598-018-32586-w
    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

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  • Language: English
    Title: Role of hypoxia-inducible factor-1 in the development of renal fibrosis in mouse obstructed kidney: Special references to HIF-1 dependent gene expression of profibrogenic molecules
    Journal name: Journal of Pharmacological Sciences  vol.136  (1)  (p.31 - 38)
    Date of publication: 2018.01
    Author(s): Kazuya Kabei, Yu Tateishi, Masakazu Nozaki, Masako Tanaka, Masayuki Shiota, Mayuko Osada-Oka, Shunji Nishide, Junji Uchida, Tatsuya Nakatani, Shuhei Tomita, Katsuyuki Miura

    DOI: 10.1016/j.jphs.2017.12.004
    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

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