Personnel Information

写真b

OOTANI Kiyoshi

Organization
School of Biological and Environmental Sciences Department of Biomedical Sciences
Research Fields, Keywords
生命医化学
Teaching and Research Fields
細胞増殖制御、癌化、転写制御
SDGs Related Goals

Degree 【 display / non-display

  • Degree name:Medical Doctor
    Classified degree field:Life Science / Human pathology
    Conferring institution:Tohoku University
    Acquisition way:Coursework
    Date of acquisition:1989.03

Career 【 display / non-display

  • Affiliation:Kwansei Gakuin University
    Title:Professor
    Date:2009.04 -

Association Memberships 【 display / non-display

  • Academic society name:日本分子生物学会
    Academic country located:Japan

  • Academic society name:日本癌学会
    Academic country located:Japan

  • Academic society name:日本ウイルス学会
    Academic country located:Japan

Research Areas 【 display / non-display

  • Research field:Life Science / Molecular biology

Papers 【 display / non-display

  • Language: English
    Title: Ectopic expression of CDK inhibitor p21Cip1 upregulates deregulated E2F activity and enhances cancer cell-specific cytotoxic gene expression mediated by ARF tumor suppressor promoter.
    Journal name: Biochem Biophys Res Commun  vol.483  (p.107 - 114)
    Date of publication: 2017.01
    Author(s): Kurayoshi K, Shiromoto A, Ozono E, Iwanaga R, Bradford AP, Araki K and Ohtani K

    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

  • Language: English
    Title: The phosphatidyl inositol 3 kinase pathway does not suppress activation of the ARF and BIM genes by deregulated E2F1 activity.
    Journal name: Biochem Biophys Res Commun  vol.482  (p.784 - 790)
    Date of publication: 2017.01
    Author(s): Kurayoshi K, Okuno J, Ozono E, Iwanaga R, Bradford AP, Kugawa K, Araki K, Ohtani K

    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

  • Language: English
    Title: The interaction mode of the acidic region of the cell cycle transcription factor DP1 with TFIIH.
    Journal name: J Mol Biol  vol.428  (p.4993 - 5006)
    Date of publication: 2016.12
    Author(s): Okuda M, Araki K, Ohtani K, Nishimura Y

    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

  • Language: English
    Title: Identification of novel target genes specifically activated by deregulated E2F in human normal fibroblasts.
    Journal name: Genes Cells  vol.20  (p.739 - 757)
    Date of publication: 2015.09
    Author(s): Kitamura H, Ozono E, Iwanaga R, Bradford AP, Okuno J, Shimizu E, Kurayoshi K, Kugawa K, Toh H, Ohtani K.

    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

  • Language: English
    Title: Cancer cell specific cytotoxic gene expression mediated by ARF tumor suppressor promoter constructs.
    Journal name: Biochem Biophys Res Commun  vol.450  (p.240 - 246)
    Date of publication: 2014.07
    Author(s): Kurayoshi K, Ozono E, Iwanaga R, Bradford AP, Komori H, Ohtani K.

    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

display all >>

Industrial Property Rights 【 display / non-display

  • Property type:Patent
    Title:がん細胞標的ベクター、がん細胞特異的に目的遺伝子を発現させる方法及びがん細胞特異的に目的遺伝子を発現させるための使用
    Inventor(s)/Creator(s):大谷清

    Application number:特願2016-514831, 2015.03.27
    Country:Japan

  • Property type:Patent
    Title:がん細胞標的ベクター、がん細胞特異的に目的遺伝子を発現させる方法及びがん細胞特異的に目的遺伝子を発現させるための使用
    Inventor(s)/Creator(s):大谷清

    Application number:PCT/JP2015/059699, 2015.03.27
    Country:

Research Projects 【 display / non-display

  • Research category:Grant-in-Aid for Scientific Research(C)
    Project year:2021.04 - 2024.03
    Title:がん化抑制に重要なRBの制御を外れたE2F1活性の制御メカニズムの解明

  • Research category:Grant-in-Aid for Scientific Research(C)
    Project year:2015.04 - 2018.03
    Title:転写因子E2Fによる細胞増殖とがん化抑制の仕分け機構の解明

      Show links to external sites

  • Project year:2012.11 - 2013.10
    Title:がん細胞特異性のより高いがん細胞傷害性組換えアデノウイルスの開発(研究成果展開事業 研究成果最適展開支援プログラムA-STEP探索タイプ)
    Awarding organization:独立行政法人科学技術振興機構

  • Research category:Grant-in-Aid for Scientific Research(C)
    Project year:2012.04 - 2015.03
    Title:転写因子E2Fによるがん化抑制機構の解析

      Show links to external sites

  • Research category:Grant-in-Aid for Scientific Research(C)
    Project year:2009.04 - 2012.03
    Title:細胞増殖と癌化抑制における転写因子E2Fによる細胞運命決定機構の解析

      Show links to external sites