Personnel Information

写真b

SHIBATA Yukimasa

Organization
School of Biological and Environmental Sciences
Research Fields, Keywords
発生生物学 エピジェネティクス 遺伝子発現調節, Developmental Biology
Teaching and Research Fields
動物には脳や心臓、皮膚、筋肉など色々な組織があり、これらは様々な種類の細胞が作られています。では、たった一種類の受精卵から、これらの様々な種類の細胞を作るにはどんな、仕組みが必要なのでしょうか。一つの受精卵が分裂し、様々な種類の細胞を作る過程で個々の細胞はそれぞれ違った経験をします。細胞は自分がたどった履歴を記憶する事で、個性を獲得し、その情報に基づいて遺伝子を発現する事で細胞同士の違いを生み出します。
 私は、この細胞の履歴を核に記録し、それに基づいて遺伝子発現を調節するための仕組みを研究しています。この仕組みがある事で、皆さん自身の体の全ての細胞が同じDNAや遺伝子を持っているにもかかわらず、それぞれの細胞は異なるセットの遺伝子を発現し、神経は神経の、表皮は表皮の特性(細胞運命)を維持し続ける事ができるのです。私は、分化した細胞が運命を維持するための仕組みを解き明かすために、モデル生物、線虫C. elegansを用いて遺伝学的なアプローチで研究を進めています。
SDGs Related Goals

Graduating School 【 display / non-display

  • Graduating School:Nagoya University
    Faculty:Faculty of Science
    Course / Major:分子生物学科

    Kind of school:University
    Date of graduation:1994.03
    Completion status:Graduated
    Country location code:Japan

Graduate School 【 display / non-display

  • Graduate school:Nagoya University
    Department:Graduate School, Division of Natural Science

    Course completed:Doctor's Course
    Date of completion:1999.03
    Completion status:Completed
    Country:Japan

Degree 【 display / non-display

  • Degree name:博士(理学)
    Classified degree field:Life Science / Molecular biology
    Conferring institution:Nagoya University
    Acquisition way:Coursework
    Date of acquisition:2000.02

Career 【 display / non-display

  • Affiliation:Kwansei Gakuin University
    Department:School of Biological and Environmental Sciences
    Title:Assistant Professor
    Date:2022.04 -

  • Affiliation:Kwansei Gakuin University
    Department:School of Science and Technology
    Title:Assistant Professor
    Date:2014.05 - 2018.11

  • Affiliation:Kwansei Gakuin University
    Department:Graduate School of Science and Technology
    Title:Postdoctoral Fellow
    Date:2010.10 - 2014.04

  • Title:Researcher
    Date:2003.04 - 2010.09

  • Title:Postdoctoral Fellow
    Date:2000.04 - 2003.03

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Association Memberships 【 display / non-display

  • Academic society name:日本分子生物学会
    Academic country located:Japan

  • Academic society name:日本発生生物学会
    Academic country located:Japan

Research Areas 【 display / non-display

  • Research field:Life Science / Developmental biology

Papers 【 display / non-display

  • Language: English
    Title: Repulsive guidance molecule acts in axon branching in Caenorhabditis elegans
    Journal name: SCIENTIFIC REPORTS  vol.11  (1)
    Date of publication: 2021.11
    Author(s): Tsutsui Kaname, Kim Hon-Song, Yoshikata Chizu, Kimura Kenji, Kubota Yukihiko, Shibata Yukimasa, Tian Chenxi, Liu Jun, Nishiwaki Kiyoji

    DOI: 10.1038/s41598-021-01853-8
    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

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  • Language: English
    Title: Genetic interactions among ADAMTS metalloproteases and basement membrane molecules in cell migration in Caenorhabditis elegans
    Journal name: PLOS ONE  vol.15  (12)
    Date of publication: 2020.12
    Author(s): Imanishi Ayaka, Aoki Yuma, Kakehi Masaki, Mori Shunsuke, Takano Tomomi, Kubota Yukihiko, Kim Hon-Song, Shibata Yukimasa, Nishiwaki Kiyoji

    DOI: 10.1371/journal.pone.0240571
    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

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  • Language: English
    Title: Maintenance of cell fates and regulation of the histone variant H3.3 by TLK kinase in Caenorhabditis elegans
    Journal name: BIOLOGY OPEN  vol.8  (1)
    Date of publication: 2019.01
    Author(s): Shibata Yukimasa, Seki Yoshiyuki, Nishiwaki Kiyoji

    DOI: 10.1242/bio.038448
    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

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  • Language: English
    Title: Organ Length Control by an ADAMTS Extracellular Protease in Caenorhabditis elegans
    Journal name: G3-GENES GENOMES GENETICS  vol.6  (5)  (p.1449 - 1457)
    Date of publication: 2016.05
    Author(s): Shibata Yukimasa, Kawakado Yuri, Hori Noriyoshi, Tanaka Kota, Inoue Ryo, Takano Tomomi, Kubota Yukihiko, Nishiwaki Kiyoji

    DOI: 10.1534/g3.116.028019
    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

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  • Language: English
    Title: The BED finger domain protein MIG-39 halts migration of distal tip cells in Caenorhabditis elegans
    Journal name: DEVELOPMENTAL BIOLOGY  vol.397  (2)  (p.151 - 161)
    Date of publication: 2015.01
    Author(s): Kikuchi Tetsuhiro, Shibata Yukimasa, Kim Hon-Song, Kubota Yukihiko, Yoshina Sawako, Mitani Shohei, Nishiwaki Kiyoji

    DOI: 10.1016/j.ydbio.2014.10.008
    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

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Research Projects 【 display / non-display

  • Research category:Grant-in-Aid for Research Activity start-up
    Project year:2022.08 - 2024.03
    Title:基底膜による老化抑制機構の研究

  • Research category:Grant-in-Aid for Scientific Research(C)
    Project year:2016.04 - 2019.03
    Title:分化した細胞で働く運命維持機構の解明

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  • Research category:Grant-in-Aid for Young Scientists(B)
    Project year:2011.04 - 2014.03
    Title:細胞運命維持におけるヒストンアセチル化を介した転写抑制維持機構の研究

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Presentations 【 display / non-display

  • Language:Japanese
    Conference name:日本生物工学会大会講演要旨集
    International/Domestic presentation:Domestic presentation
    Holding date:2014.08
    Title:1P-087 Effect of branched-chain polyamine on C. elegans growth
    Presentation type:Poster presentation

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  • Conference name:elegans, Development v.137
    International/Domestic presentation:Domestic presentation
    Holding date:2010
    Title:Double bromodomain protein BET-1 and MYST HATs establish and maintain stable cell fates in C.
    Presentation type:Oral presentation (general)

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  • Conference name:Development
    International/Domestic presentation:Domestic presentation
    Holding date:2010
    Title:Double bromodomain protein BET-1 and MYST HATs establish and maintain stable cell fates in C.elegans
    Presentation type:Oral presentation (general)

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  • Language:Japanese
    Conference name:日本分子生物学会年会プログラム・講演要旨集
    International/Domestic presentation:Domestic presentation
    Holding date:1998.12
    Title:An Analysis of loc-1 Gene Involved in Suppression of the Activity
    Presentation type:Oral presentation (general)

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