Personnel Information

写真b

OKIYONEDA Tsukasa

Organization
School of Biological and Environmental Sciences Department of Biomedical Sciences
Research Fields, Keywords
分子細胞生物学, 生化学, 薬理学
Profile
膜タンパク質、タンパク質品質管理、難治性疾患、自然免疫
Syllabus information URL
https://syllabus.kwansei.ac.jp/uniasv2/UnSSOLoginControlFree?REQ_ACTION_DO=/AGA030PLS01Action.do?REQ_FUNCTION_JUMP_START_FLG=1&SLB_LINK_DISP_FLG=305&TCH_NO=130013&REQ_PRFR_FUNC_ID=AGA030
SDGs Related Goals
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Graduating School 【 display / non-display 】

  • Graduating School:Kumamoto University
    Faculty:Faculty of Pharmaceutical Science

    Kind of school:University
    Date of graduation:1998.03
    Completion status:Graduated
    Country location code:Japan

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Graduate School 【 display / non-display 】

  • Graduate school:Kumamoto University
    Department:Graduate School, Division of Pharmaceutical Sciences

    Course completed:Doctor's Course
    Date of completion:2003.03
    Completion status:Completed
    Country:Japan

  • Graduate school:Kumamoto University
    Department:Graduate School, Division of Pharmaceutical Sciences

    Course completed:Master's Course
    Date of completion:2000.03
    Completion status:Completed
    Country:Japan

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Studying abroad experiences 【 display / non-display 】

  • Name of institution: McGill University
    Name of job or career: リサーチアソシエイト
    Date: 2008.06 - 2013.03

  • Name of institution: Hospital for Sick Children Research Institute
    Name of job or career: 博士研究員
    Date: 2006.04 - 2008.05

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Degree 【 display / non-display 】

  • Degree name:薬学博士
    Classified degree field:Life Science / Pharmaceutical hygiene and biochemistry
    Conferring institution:Kumamoto University
    Acquisition way:Coursework
    Date of acquisition:2003.03

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Career 【 display / non-display 】

  • Affiliation:Kwansei Gakuin University
    Department:School of Science and Technology Department of Biomedical Chemistry
    Title:Professor
    Date:2019.04 -

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Association Memberships 【 display / non-display 】

  • Academic society name:日本分子生物学会
    Academic country located:Japan

  • Academic society name:日本薬学会
    Academic country located:Japan

  • Academic society name:日本生化学会
    Academic country located:Japan

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Research Areas 【 display / non-display 】

  • Research field:Life Science / Pharmacology

  • Research field:Life Science / Functional biochemistry

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Qualification acquired 【 display / non-display 】

  • Qualification title:Pharmacist

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Papers 【 display / non-display 】

  • Title: The COPD-Associated Polymorphism Impairs the CFTR Function to Suppress Excessive IL-8 Production upon Environmental Pathogen Exposure
    Journal name: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES  vol.24  (3)
    Date of publication: 2023.02
    Author(s): Hinata Daichi, Fukuda Ryosuke, Okiyoneda Tsukasa

    DOI: 10.3390/ijms24032305

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  • Title: The Ubiquitin Ligase RNF34 Participates in the Peripheral Quality Control of CFTR (RNF34 Role in CFTR PeriQC)
    Journal name: Frontiers in Molecular Biosciences  vol.9
    Date of publication: 2022
    Author(s): Okiyoneda Tsukasa

    DOI: 10.3389/fmolb.2022.840649

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  • Title: Efficient induction of proximity-dependent labelling by biotin feeding in BMAL1-BioID knock-in mice
    Journal name: JOURNAL OF BIOCHEMISTRY  vol.170  (4)  (p.453 - 461)
    Date of publication: 2021.10
    Author(s): Murata Kazuya, Mimura Asuka, Suzuki Hayate, Mikami Natsuki, Hamada Yuko, Kato Kanako, Iki Natsumi, Ishida Miyuki, Daitoku Yoko, Tanimoto Yoko, Okiyoneda Tsukasa, Fujiyama Tomoyuki, Dinh Tra Thi Huong, Mizuno Seiya, Sugiyama Fumihiro

    DOI: 10.1093/jb/mvab059

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  • Language: English
    Title: Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitylation as a Novel Pharmaceutical Target for Cystic Fibrosis
    Journal name: Pharmaceuticals (Basel)  vol.13  (75)
    Date of publication: 2020.04
    Author(s): Ryosuke Fukuda, Tsukasa Okiyoneda

    DOI: doi: 10.3390/ph13040075
    Type of publication: Research paper (scientific journal)
    Co-author classification: Multiple Authorship

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  • Title: Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitylation as a Novel Pharmaceutical Target for Cystic Fibrosis
    Journal name: PHARMACEUTICALS  vol.13  (4)
    Date of publication: 2020.04
    Author(s): Fukuda Ryosuke, Okiyoneda Tsukasa

    DOI: 10.3390/ph13040075

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MISC 【 display / non-display 】

  • Language:Japanese
    Title:嚢胞性線維症原因遺伝子産物CFTRの品質管理機構と機能制御
    Publisher:公益社団法人日本生化学会
    Journal name:生化学  vol.92  (2)  (p.179 - 188)
    Date of publication:2020.04
    Author(s):福田 亮介，沖米田 司

    DOI:doi:10.14952/SEIKAGAKU.2020.920179
    Type of publication:Article, review, commentary, editorial, etc. (bulletin of university, research institution)

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  • Language:Japanese
    Title:嚢胞性線維症のユビキチン創薬
    Journal name:ファルマシア
    Date of publication:2020.01
    Author(s):沖米田司

    Type of publication:Article, review, commentary, editorial, etc. (scientific journal)

  • Language:Japanese
    Title:嚢胞性線維症における上皮細胞の水の輸送障害を理解する
    Journal name:消化器病学サイエンス  vol.3  (2)  (p.82 - 86)
    Date of publication:2019
    Author(s):福田亮介, 沖米田司

    Type of publication:Article, review, commentary, editorial, etc. (scientific journal)

  • Language:Japanese
    Title:異常な形質膜タンパク質を除去する新しい品質管理機構
    Journal name:生化学  vol.86  (1)  (p.54 - 58)
    Date of publication:2014.02
    Author(s):沖米田司

    Type of publication:Article, review, commentary, editorial, etc. (scientific journal)

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Industrial Property Rights 【 display / non-display 】

  • Property type:Patent
    Title:嚢胞性線維症予防又は治療剤
    Inventor(s)/Creator(s):沖米田司

    Application number:PCT/JP2018/009524, 2018.03.12
    Publication number:WO2018/168777, 2018.09.20
    Country:Japan

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Research Projects 【 display / non-display 】

  • Research category:Grant-in-Aid for Scientific Research(B)
    Project year:2022.04 - 2025.03
    Title:哺乳類 ERAD における逆輸送機構の包括的理解

  • Research category:Grant-in-Aid for Scientific Research on Innovative Areas (Research in a Proposed Research Area)
    Project year:2021.04 - 2023.03
    Title:CFTR ユビキチン化制御剤の創出と CF 創薬への応用

  • Research category:Grant-in-Aid for Scientific Research(B)
    Project year:2019.04 - 2022.03
    Title:PMQCにおけるユビキチン化制御分子の機能解明と治療的応用

  • Research category:Grant-in-Aid for Scientific Research(B)
    Project year:2019.04 - 2022.03
    Title:PMQCにおけるユビキチン化制御分子の機能解明と治療的応用

  • Research category:Grant-in-Aid for Scientific Research on Innovative Areas (Research in a Proposed Research Area)
    Project year:2019.04 - 2021.03
    Title:RFFL による形質膜タンパク質品質管理作動機構の解明と CF 創薬への応用

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Presentations 【 display / non-display 】

  • Language: English
    Conference name: ConBio2017
    International/Domestic presentation: International presentation
    Holding date: 2017.12

    Title: 形質膜CFTRの選択的単離法の確立と結合タンパク質の網羅的解析
    Presentation type: Poster presentation

  • Language: English
    Conference name: ConBio2017
    International/Domestic presentation: Domestic presentation
    Holding date: 2017.12

    Title: 形質膜タンパク質品質管理に関わるエンドソーム局在ユビキチンリガーゼの機能解析
    Presentation type: Poster presentation

  • Language: English
    Conference name: ConBio2017
    International/Domestic presentation: Domestic presentation
    Holding date: 2017.12

    Title: 異なる細胞内分解経路に関わる CFTR 変異体のポリユビキチン化修飾解析
    Presentation type: Poster presentation

  • Language: English
    Conference name: ConBio2017
    International/Domestic presentation: Domestic presentation
    Holding date: 2017.12

    Title: ドラッグリポジショニングによるCFTRコレクターの開発
    Presentation type: Poster presentation

  • Language: English
    Conference name: 第９０回日本薬理学会年会　シンポジウム
    International/Domestic presentation: Domestic presentation
    Holding date: 2017.03

    Title: Ubiquitination mechanism as a novel drug target for cystic fibrosis
    Presentation type: Oral presentation (invited, special)

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Committee Memberships 【 display / non-display 】

  • Organization name:日本生化学会
    Committee name:生化学誌 企画協力委員
    Date:2014.01 -

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Social Contribution 【 display / non-display 】

  • Title:平成29年度JSPSサマー・プログラム　留学生受入
    Date:2017.06 - 2017.08

  • Title:熊本大学薬学部　大学院セミナー
    Date:2014.12

  • Title:関西学院創立125周年 世界市民フォーラムin大阪 「いま、科学技術を学ぶということ～ボーダーレス化する知の世界～」
    Date:2014.07

  • Title:関西学院大学オープンラボ「免疫の力を使って、病原体を見つけよう！」ひらめき☆ときめきサイエンス事業
    Date:2014.07

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